UK parliament gives three-parent IVF the go-ahead


In a world first, members of the UK parliament have voted to allow mitochondrial donation.


The procedure will allow women with genetic faults in their mitochondria – the cell's energy generators – to have children without fear of passing on their faulty mitochondrial DNA. It involves transferring the nucleus of the mother's egg or fertilised embryo into an egg from an unrelated donor. The resulting child will inherit their nuclear DNA from their parents and their mitochondrial DNA from the donor. Because the change to the mitochondrial DNA is permanent, the technique will not only prevent the child inheriting mitochondrial disease but also any of their descendants.


The vote passed with 382 in favour and 128 against. During the preceding debate, health minister Jane Ellison told parliament: "This is a bold step but it's an informed step, and for the families involved it's a light at the end of a very long tunnel."


The shadow health minister Luciana Berger also threw her weight behind the procedure, saying: "There will always have to be a leap of faith the first time it's used in humans… but I believe we must not delay any further." The former Minister for Universities and Science David Willletts emphasised to MPs that mitochondrial DNA does not play a role in shaping the character or personality of the person. "The red line is where we change the nuclear DNA," he said.



Among others, descent came from the Conservative MP Fiona Bruce who worried that the genetic alterations will be passed down to future generations – "once the alteration has taken place, there is no going back, for society or the children involved," she said.


No evidence it is unsafe


At a public debate last night, Andy Greenfield, a member of an independent panel convened by the UK Human Fertilisation and Embryology Authority (HFEA) to advise the government, revealed that new, unpublished data gave added reassurance that the procedure would be safe. The research was carried out by a team at Newcastle University, UK, that has been pioneering one of the replacement techniques since 2000.


Their new work comes on the back of three scientific reviews, an ethics review and a public consultation overseen by the HFEA. Frances Flinter, professor of genetics at King's College London, told the debate: "We can't guarantee the intervention will be safe, but we can tell couples that we have no evidence it will be unsafe."


The Newcastle group estimates that the procedure could help 2473 women in the UK, and 12,423 women in the US, aged between 15 and 44 years. This equates to an average of 152 births per year in the UK, and 778 births per year in the US.


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New Urbanist: The ghosts that keep your house safe



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New Urbanist is a monthly column that explores how technology and design are changing our cities, homes, the built environment – and ourselves


Last month at the Consumer Electronics Show in Las Vegas, Edith Ramirez, chairwoman of the US Federal Trade Commission, warned her audience that "2015 will be the year we start hearing about smart-home hacking".


Indeed, as internet-connected devices proliferate in our homes, a minor arms race has emerged that is fundamentally transforming the landscape of domestic security. From networked personal surveillance cameras to cloud-accessible front door locks, these new devices offer powerful tools to keep us safe – but they also reveal complex and unanticipated vulnerabilities.


Perhaps the simplest of these crime-fighting gadgets are Hollywood-style special effects, or multimedia tools for suggesting that someone is still at home. The illusion that a home is inhabited – that the residents are not out for a day of shopping or college football – becomes especially important when it is so easy to track where people are using social media. Your Twitter feed says you're down at the beach – but someone appears to be changing the channel on your bedroom television. Is anyone home or not?


Screen simulator


Consider a product known as FakeTV, which is really nothing more than a programmable toy: its flashing screen "simulates the light of a 27-inch LCD television", according to the ad copy, making it "perfect for bedrooms".



FakeTV is just a contemporary upgrade of the table lamp on a timer for our screen-addicted age, but another product called BeON brings us fully into the era of the smart home. The outcome of a recently successful Kickstarter campaign, it is an LED light that not only memorises but also reproduces your typical lighting behaviours so it appears that you are still at home. The BeON will even run through an archive of previously saved sequences so that, if the doorbell rings, for example, various lights will click on or off inside the home, making it appear as if you might be approaching the front door.


This is a new age of algorithmic security, when the home itself becomes a partially automated system preprogrammed with human-like behaviours. In effect, fear of crime and a desire to prevent burglary are transforming the domestic interior into an uninhabited multimedia environment, an immersive videodrome playing randomised loops that can be mistaken for human behaviour.


Deceptive sound effects


Ingenuity knows no limit when it comes to the frontiers of home security. For example, there are already albums of background noise available to make it sound as if someone is rummaging through the refrigerator or watching TV in the other room. One collection specifically promises "hundreds of professionally recorded interior house sounds to give the realistic impression that someone is at home". It won't be long before audio effects such as these are integrated directly into a FakeTV-like system, playing deceptive sounds through hidden speakers in an otherwise empty house or apartment.


The future of home security looks to be an environment populated by multimedia phantoms and A/V ghosts, an algorithmic cinema of human domesticity. There is, of course, something uncanny in this suggestion that our behaviour can now be reproduced simply by a series of lights and screens being turned on and off at particular times of day.


To be sure, these mimicked rhythms are meant only to fool burglars, but this nonetheless speaks volumes about our current anthropological state. An entire family can now be halfway around the world, but even their closest neighbours may be deceived by the appearance of an iPad sleeplessly glowing in the master bedroom.


Home CCTV


Combating burglars with the latest in high-tech is not all about deception, however. Home surveillance is entering its own golden age, with networked systems such as Dropcam bringing the near-ubiquitous presence of CCTV right into the modern home.


Dropcam is a system of internet-connected "smart" cameras that record both audio and video data, and even come with night vision. What's so perversely brilliant about Dropcam's marketing is that the cameras are presented less as security tools and more as something like the ultimate family scrapbook, recording every conceivable moment within the house.


Why take photos at all, in other words, when an automated, ubiquitous system of home surveillance does it all for you? "Never miss a moment," the company says. We have arrived at the era of the at-home Panopticon by way of the family photo album.


The irony of this is that the security risks posed by cloud-based home camera systems are both obvious and significant. Tools such as FakeTV and BeON lights are utterly useless, for example, if a burglar can simply hack into your Dropcam footage and see if someone is actually home. Worse, leaked celebrity smartphone photos are one thing; imagine hackers broadcasting a live feed of your favourite actor's personal Dropcam network to millions of people around the world.


The twisted beauty of the home-security market is such that these risks only present rich opportunities for other tech-minded entrepreneurs. Worried that someone may hack your in-home camera network to discover that you're really not around? In the years to come, perhaps we'll see CGI homeowners digitally airbrushed into their own video footage, as if someone is curled up reading an e-book or watching TV. It's only a small step from there to imagining that interactive holograms visible from the street will be the next must-have feature of a 21st-century burglar alarm.



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Let public have greater say over big health data


Digital data are being amassed at an astonishing rate. This vast store presents great opportunities for science. Health data – for example, from biomarkers, medical imaging and genome analysis – offer a rich resource. Combined with data about lifestyle, diet and living and working environments, they can yield new insights on the causes of disease and the effectiveness of treatments, help to predict and prevent illness and allow therapies to be personalised.


Recent advances in information technology and data science – such as faster computing and improved methods of analysis – make this increasingly possible and are already being used in projects that rely on volunteers, such as the UK Biobank, which hopes to track the lifestyle and health of 500,000 over-45s.


So why has the UK government's giant care.data scheme, which aims to aid research and improve the health service by centralising data on millions of people in England obtained from family doctors, met with such resistance?


When security and privacy doubts were voiced over care.data last year, the project was postponed. It is an active opt-out scheme; unless an individual objects, their details are included. But the reaction of GPs, the media and civil society demonstrated that the data uses intended in the scheme were not in line with people's expectations.



Data worries


People have concerns about data misuse – such as worries over insurance pricing, marketing, political surveillance and identity theft – but we do not yet have a clear understanding of the impact of such misuse. Research commissioned as part of the Nuffield Council on Bioethics's new report on the use of big data in health care and biomedical research, led by the Wellcome Trust's Expert Advisory Group on Data Access, shows that the harms are likely to be broad in range and more prevalent than those that are acknowledged by regulatory regimes. We know that a particular public concern is the sharing of health data with commercial researchers: for example, pharmaceutical or insurance companies.


Re-identification from "anonymised" data is increasingly possible as technology improves and more and more databases become linked. People are being asked to consent to data uses that have implications which neither they nor the researchers may fully understand. And simply complying with data law is not enough: it is just a framework that may not fully capture the reasonable expectations of research participants about how their data will be used.


To win public confidence, we need to go further. We need to start by understanding people's interests in how their data will be used. Appropriate security measures and participant consent need to be framed within governance systems that both involve and are accountable to those whose data is held.


Such systems must take seriously people's reasonable expectations about data use: about who may have access to the data, for what purposes and for how long. This may seem onerous, but there are examples of good practice to draw from as well as sobering lessons from previous cases.


These recommendations are in the latest report from the Nuffield Council on Bioethics. It offers a set of principles and some practical guidance to help those contemplating data initiatives such as care.data. Other conclusions include tracking how health data are used and ensuring individuals are told of any privacy breaches. Tough penalties for deliberate misuse of data, including imprisonment, should be introduced, even if it appears that no harm was caused.


Only in this way will we build the public involvement and trust that is necessary to ensure that the benefits of personal health data are not squandered.


Martin Richards is chair of the Nuffield Council on Bioethics Working Party for the report The Collection, Linking and Use of Data in Biomedical Research and Health Care: Ethical Issues. He is also emeritus professor of family research at the University of Cambridge


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Green light for mission to Jupiter moon Europa


Pack your ice gear – we're going to Europa. NASA's budget request for 2016 includes $30 million for a dedicated mission to Jupiter's icy moon, which is considered one of the best prospects for discovering life in our solar system.


Europa has been a tempting destination for planetary scientists since the mid-1990s, when the Galileo orbiter revealed that it may harbour a deep ocean of briny liquid water beneath a thick icy shell. More recently, reports that plumes of subsurface water could be venting into space sparked calls for a mission to sample that water directly and see if anything lives in it.


Last year, NASA received $100 million from Congress to begin preliminary work on such a mission, but was missing the commitment to further funding for a period long enough to plan a mission.


Now, with another $255 million budgeted over the next 5 years, NASA is giving a clearer green light. "For the first time, the budget supports the formulation and development of a Europa Mission, allowing NASA to begin project formulation," the budget request reads.



The mission will probably involve a spacecraft orbiting Jupiter and making multiple fly-bys of Europa, rather than landing on or orbiting Europa itself. This will make the mission much cheaper and safer, as Europa sits in a harsh radiation environment that can be dangerous for spacecraft. NASA will choose instruments for the spacecraft in spring this year, and aims for a launch date in the mid-2020s.


"This is a big deal," says Robert Pappalardo at NASA's Jet Propulsion Lab in Pasadena, California, the pre-project scientist for the Europa Clipper probe concept. "We're moving toward the next phase, where you're a real mission. It's just thrilling after 15 years of pushing for it. It's a great day."


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Mitochondrial replacement vote: What you need to know


The UK government is today voting on whether mitochondrial replacement techniques – three-parent babies – can be used in women who carry mitochondrial disease. If given the go-ahead, the procedure would avoid children being born with serious diseases due to mutations in mitochondrial DNA


What are mitochondria?

Mitochondria are the energy generators of our cells. They have their own DNA which is passed down by the mother and is distinct from the chromosomes in the nucleus. Mutations in the mitochondrial DNA can lead to blindness, seizures, dementia or mental impairment, and early death. There is currently no cure.


What options are there for women at risk of passing on mutated mitochondrial DNA?

They can avoid having children, or any further children if the first was affected. They can hope that their child will be OK, which is very risky. They can adopt or use egg donation, in which case the child will not be genetically related to them. Or they can use pre-implantation genetic diagnosis to look for embryos with a sufficiently low proportion of mutant mitochondrial DNA.


This, however, is not possible where there is a high proportion of abnormal mitochondrial DNA or where it is all abnormal, which is common. Mitochondrial replacement offers another option for these women.



What do the techniques involve?

It is a form of IVF that involves transferring the nucleus from the prospective mother's egg into a donor egg with healthy mitochondria, either before or after it is fertilised by the woman's partner. The resulting child will have nuclear DNA from the woman and her partner, and mitochondrial DNA from the donor.


The procedures have been successfully trialled in monkeys and if the techniques are approved for use in the UK, the regulations will be in place for clinical trials in people – a world first.


How many women could it help?

A recent study carried out by the researchers at Newcastle University pioneering the techniques estimated that 2473 women in the UK, and 12,423 women in the US, aged between 15 and 44 years, are at risk of passing on potentially lethal mitochondrial DNA to their children. This equates to an average of 152 births per year in the UK, and 778 births per year in the US.


But because the change to the mitochondrial DNA is permanent, the technique will not only prevent the child inheriting mitochondrial disease but also any of their descendants.


Why is the procedure so controversial?

For a number of reasons. First, there's the fact that the child will inherit DNA from three people. For many, this isn't an issue because the donor's mitochondria contribute just 37 genes to the child, compared with more than 20,000 from the parents. That's a negligible amount, and far less than you would gain from a blood transfusion or organ transplant.


We know that mitochondria do more than simply power our cells, but in a recent New Scientist piece, Robin Lovell-Badge from the MRC National Institute for Medical Research in London explained why none of these "extra" functions are relevant to mitochondrial replacement.


Then there are concerns that changes to the mitochondrial DNA might affect future generations in unknown ways. Again, most researchers think that the unintended consequences are likely to be minimal.


Are we ready to allow mitochondrial replacement?

This is what the Members of Parliament will be debating today. For the past four years, an independent panel convened by the UK Human Fertilisation and Embryology Authority (HFEA) has been providing advice to the government. During this time, there has been several round-ups of the science as well as ethics reports and a public consultation.


In June last year, the panel said the work done so far suggested that the technique is safe enough to try in clinical trials as long as several extra experiments are carried out first and children born as a result of the technique are followed up for an extensive period. The extra assessments could be done in the next 18 months to two years after the regulation has passed.


See a timeline of the debate


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Hottest year on record ramps up the climate pressure


LAST year was the warmest on record, even though El Niño failed to show up. Most of the previous hottest years, such as 1998, have come with the warmer sea surfaces that El Niño brings.


If there ever was a warming hiatus, it is over. The long-term trend continues. The world is warming by 0.16 °C per decade.


The effects are evident: record heatwaves, as in Australia, and record floods – and snow – in many places, with Mozambique and the US the latest to feel the effects. Sea level is rising ever faster. Sea ice in the Arctic is vanishing.


But there's a blip in the big picture. The winter sea ice around Antarctica has grown slightly over the past few decades. It is not clear why (see "Thaw point: Why is Antarctica's sea ice still growing?Movie Camera").



The seas around Antarctica are hard to study, and computer models are missing some key details. Nonetheless, it is a bit of an embarrassment that climate scientists aren't sure exactly what's going on.


However, it would be wrong to take comfort from this blip – or exploit it to claim that scientists can't get their story straight. In just about every other way, the climate is changing as expected, or worse. This is not a new message, but with crunch UN climate talks coming at the end of the year, it bears repeating.


This article appeared in print under the headline "Cranking up the heat"


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Queen Elizabeth prizewinner: Put pharmacies on chips


Chemical engineer Robert Langer has won the £1 million 2015 Queen Elizabeth Prize for Engineering. The prize celebrates the engineers behind "ground-breaking innovation that has been of global benefit to humanity".


The announcement was made today at Prince Philip House in London by Lord Browne, chair of the Queen Elizabeth Prize for Engineering Foundation, in the presence of The Duke of York. The queen will present Langer with the prize at Buckingham Palace later this year.


Langer's work, particularly on controlled drug delivery, has provided the foundation for treatments for various cancers, diabetes, and many other conditions. He is now developing microchip implants for long-term controlled drug release, an innovation which promises to benefit millions of people. New Scientist spoke to him today.


Congratulations on winning this award.

Thank you very much. Really I'm honoured, somewhat shocked and humbled by getting it. I think it's a terrific prize, first of all – it's wonderful to see the UK and the queen wanting to do something for engineering.



You have made a string of groundbreaking discoveries at the interface between engineering and medicine. How did it all begin?

When I graduated in 1974 there was an oil crisis and I got 20 job offers from oil companies. One of the companies said if you can just increase the yield of this one chemical by 0.1 per cent that would be wonderful – it would be worth billions. I remember thinking that I didn't want to do that. I started looking up other things like education and medicine.


I wrote to Judah Folkman, a surgeon in Boston, and he was kind enough to offer me a job. I was the only engineer in the surgery lab; indeed I think I was the only engineer in the whole hospital, and I just saw so many medical problems there that I thought using my engineering background I could solve these problems in different and, I thought, better ways. It was almost like being a kid in an intellectual candy shop.


What did your work with Folkman involve?

He had a theory that if you could stop the growth of blood vessels, that might be a way of stopping cancer. I didn't realise, but it was a very controversial theory at the time, and what he wanted me to do was isolate the first substance that could stop blood vessels growing. We had an idea of what such a substance might be but it was a fairly large molecule.


Why was the size of this molecule a problem?

Large molecules often have short half-lives when injected into the body, because enzymes degrade them. That was true for this particular molecule too – it was quickly destroyed. I had the idea of developing polymers that could protect the molecule from being destroyed and then release them over whatever period of time you wanted. Now such an approach is used for many therapeutic molecules, for treating cancer, endometriosis, schizophrenia, type 2 diabetes, alcoholism and many other conditions.


How did you come up with microchip implants that give people doses of drugs, and what does this approach offer that others don't?

I had the idea while watching a TV show in the 90s about how computer chips were made. I thought you could actually make a chip with little wells with different doses of the same drug or different drugs – you could literally have a pharmacy on a chip. You could release the drugs using a computer program or even manually, by remote control.


The clinical trial that we did was for women with osteoporosis. They are supposed to take parathyroid hormone treatment via injections once a day, but the compliance rate is very low. With our technology, there's a little program and it's set so that every night the cover comes off one of the tiny wells containing the drug.


You could also use this technology for birth control. No contraceptive implant today lasts for more than five years and no implant can currently be turned on or off whenever the woman wants. We're designing a 17-year implant which the woman may turn off whenever she wants to conceive.


Your engineer's perspective has given you a unique view on medicine. Is the field still reluctant to embrace biotechnology?

I think there are always battles to be fought; the natural tendency of many scientists and companies is to be conservative. I also think that's true of grant reviewers. By and large, medicine is embracing new ideas but it's going to be the entrepreneurs, the new professors, the young people who are willing to think outside the box and not necessarily go down a conventional path – I think it's they who will change the future. People have to take bold steps, sometimes, in the beginning.



Profile


Robert Langer is a chemical engineer at the Massachusetts Institute of Technology. A renowned inventor, he is the engineer with the most cited research papers ever and a pioneer in bioengineering, drug-delivery technology, tissue engineering and nanotechnology.



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Thaw point: Why is Antarctica's sea ice still growing?


In the waters around the warming continent, the icy grip of winter seems stronger than ever. We explore the mystery of the Southern Ocean sea ice


The world is set to defrost. All over the planet glaciers are retreating, while tundra thaws. The ice caps of Greenland and Antarctica are looking fragile, and the Arctic's once-vast raft of sea ice is shrinking at an alarming pace. And down south, in the seas around Antarctica, the sea ice... well... er... seems to be growing.


In the few decades we have had satellites keeping watch, the area of the Southern Ocean covered by sea ice in winter has grown bigger, hitting record levels in recent years. The increase is small, but it is surprising – and something of a mystery. "The Arctic is doing exactly what we would expect," says Paul Holland of the British Antarctic Survey. "The Antarctic is not."


A ...


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Formation-flying birds swap places to share out lift


It's a familiar sight: a flock of birds flying overhead in a classic V-formation, each saving energy by stealing lift from the bird flying ahead. But what's in it for the bird out front?


For northern bald ibises, it's all about taking turns. The leading bird soon swaps places with the bird immediately behind it, in a rare example of a phenomenon called reciprocal altruism.


To understand how birds cooperate in flight, Bernhard Voelkl at the University of Oxford and his team tagged every ibis in a group of 14 with high-precision GPS data loggers, allowing them to measure each individual's position in relation to the rest of the flock.


Sharing duties


They found that individual birds changed positions frequently, and were only in an aerodynamically helpful position about a third of the time. Most of these formations comprised just two birds sharing duties equally.



"For whichever combination of two birds we looked at, we saw that the time bird A was flying in front of bird B matched closely the time bird B was flying in front of bird A," says Voelkl.


And this wasn't just an average over the 39 kilometres that the flock flew – Voelkl's team frequently observed swaps within a pair happening within seconds, with the leader moving back behind the same bird for a similarly timed spell of following.


"This immediacy of the reciprocation reduces the opportunity for cheating," says Voelkl. "Direct swaps also mean that you do not have to memorise who is 'owing' you leading time, so doesn't require a lot of memory."


You scratch my back…


The results strongly suggest that the birds are returning favours in turn, showing what is known as reciprocal altruism. Robert Trivers proposed this idea in 1971 to explain how organisms could help each other without being exploited by cheats. But examples of it have been hard to find and difficult to prove.


"Convincing examples of reciprocation in animals are rare," says Malte Andersson at the University of Gothenburg in Sweden, who praises the team's technique for studying ibis interactions as ingenious.


Until now, vampire bats have provided one of the few good examples of reciprocal altruism in animals. When a starving bat has not been able to feed enough to survive the night, other bats regurgitate some of their food for it and share their blood meals.


Although grooming in primates might appear to be another example, this kind of cooperation is often more likely in more closely related individuals, so is in fact associated with kin selection: the giving of favours to individuals that carry a large share of your genes.


In ibises, more than 60 per cent of the aerodynamically beneficial formations formed by the birds consisted of a single pair, with one member flying in front of the other.


Easier for two


"It is easier for two animals to cooperate together," says Voelkl. Larger groups of cooperating animals are well known to be more unstable and subject to cheating, he says.


Individual birds often left one pair to form another – most birds did not spend more than 10 per cent of their time with one specific individual – but Voelkl's team observed that some birds were more likely to pair with certain individuals than others, and that whether two birds were related had no effect on their likelihood of pairing up.


Hannes Rusch at the University of Giessen in Germany says it is particularly interesting that in the air, birds seem to cooperate in pairings that do not match relationships seen in the birds' behaviour on the ground. He suggests this indicates the birds have evolved a form of cooperation specific to flight.


Journal reference: PNAS, DOI: 10.1073/pnas.1413589112


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What makes us altruistic – and what's it good for?




Does giving money to people who beg constitute true altruism? (Image: Giacomo Pirozzi/Panos)


Two new books use the latest brain science to figure out what makes us behave selflessly – and also suggest practical steps for encouraging it


IN 1851, Auguste Comte, the French philosopher and father of sociology, coined the word altruisme (from the Latin for "others") as part of a drive to create a non-religious religion, based on scientific principles.


He defined it as "intentional action, ultimately for the welfare of others that entails at least the possibility of either no benefit or a loss to the actor", recognising it as one of the two most important findings of modern science, with the discovery of the motion of Earth. At that time, studies of animal behaviour and phrenology led him to locate egotistical instincts at the back of the brain, altruistic ones at the front.



Today, we have a far more sophisticated knowledge of the neurological and biochemical factors that underpin benevolent behaviour. And this science forms the bedrock of two books aimed at general readers – but also at those who, despite the research, still doubt the existence of altruism.


However, the books may end up inadvertently providing more ammunition for the naysayers. Take The Altruistic Brain by neuroscientist Donald Pfaff. On solid scientific ground, he builds a five-step theory of how altruism occurs, which hinges on an idea that is both unconvincing and counterproductive. Pfaff argues that to act altruistically you should first visualise the recipient of your goodwill, then mentally transform their image into your own, "from angle to angle and curve to curve". How narcissistic!


At the core of evolutionary biologist David Sloan Wilson's Does Altruism Exist? is another contentious idea: altruism has evolved as the result of group selection. But Wilson argues his corner masterfully, providing a pithy riposte to the belief that natural selection occurs only at the level of the selfish gene: "Selfishness beats altruism within groups. Altruistic groups beat selfish groups," he says.


In other words, we cooperate when doing so gives our team the edge. That doesn't sound very selfless either.


Wilson acknowledges this, but argues that thoughts and feelings are less important than actions. According to evolutionary theory, pure altruists do exist, but it doesn't matter why people choose to help others – their reasons may be opaque even to themselves. What matters is that humans can coordinate their activities in just the right way to achieve common goals. Other animals do this too, but we are masters. "Teamwork is the signature adaptation of our species," he says.


Pfaff goes further, insisting that our brain biology "compels us to be kind". He believes this knowledge alone will inspire individuals to be more altruistic. His desire to create a better world is admirable and some of his ideas are interesting, but Wilson's analysis is more coherent and nuanced.


While it is in our nature to be altruistic, Wilson says, we also have a healthy regard for self-interest and a resistance to being pushed around. Which predisposition comes to the fore depends on the environment in which we find ourselves. Ethics, he says, cannot be taught at individual level, but are "a property of the whole system".


Wilson's fascinating gallop through religion, economics, politics and everyday life reveals many ways to activate altruism. Take his Neighborhood Project, where he designs environments to select for prosocial behaviour. By doing this, he and others promote measures to help groups function better, by, say, encouraging equality or discouraging free-riding. Not pure altruism, sure, but sound science. Comte would be impressed.


This article appeared in print under the headline "The greater good"


Issue 3006 of New Scientist magazine


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